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Repair of ionizing radiation-induced DNA double strand breaks by non-homologous end-joining
DNA double strand breaks (DSBs) are considered the most cytotoxic type of DNA lesion. They can be introduced by external sources such as ionizing radiation (IR), by chemotherapeutic drugs such as topoisomerase poisons and by normal biological processes such as V(D)J recombination. If left unrepaired...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975036/ https://ncbi.nlm.nih.gov/pubmed/19133841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20080413 |
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