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Repair of Double-Strand Breaks by End Joining

Nonhomologous end joining (NHEJ) refers to a set of genome maintenance pathways in which two DNA double-strand break (DSB) ends are (re)joined by apposition, processing, and ligation without the use of extended homology to guide repair. Canonical NHEJ (c-NHEJ) is a well-defined pathway with clear ro...

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Detalhes bibliográficos
Main Authors: Chiruvella, Kishore K., Liang, Zhuobin, Wilson, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632057/
https://ncbi.nlm.nih.gov/pubmed/23637284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a012757
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