DNA double strand break repair via non-homologous end-joining

DNA double-stranded breaks (DSB) are among the most dangerous forms of DNA damage. Unrepaired DSBs results in cells undergoing apoptosis or senescence whereas mis-processing of DSBs can lead to genomic instability and carcinogenesis. One important pathway in eukaryotic cells responsible for the repa...

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Bibliographic Details
Main Authors: Davis, Anthony J., Chen, David J.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758668/
https://ncbi.nlm.nih.gov/pubmed/24000320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2218-676X.2013.04.02
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