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DNA double strand break repair via non-homologous end-joining
DNA double-stranded breaks (DSB) are among the most dangerous forms of DNA damage. Unrepaired DSBs results in cells undergoing apoptosis or senescence whereas mis-processing of DSBs can lead to genomic instability and carcinogenesis. One important pathway in eukaryotic cells responsible for the repa...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3758668/ https://ncbi.nlm.nih.gov/pubmed/24000320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2218-676X.2013.04.02 |
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