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Detection and repair of ionizing radiation induced DNA double strand breaks: new developments in non-homologous end joining
DNA double-strand breaks (DSBs) are considered the most cytotoxic form of DNA damage. In human cells, the major pathway for the repair of ionizing radiation (IR)-induced DSBs is non-homologous end joining (NHEJ). Here we discuss recent developments in our understanding of the mechanism of NHEJ, the...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3731128/ https://ncbi.nlm.nih.gov/pubmed/23433795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2013.01.011 |
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