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Detection and repair of ionizing radiation induced DNA double strand breaks: new developments in non-homologous end joining

DNA double-strand breaks (DSBs) are considered the most cytotoxic form of DNA damage. In human cells, the major pathway for the repair of ionizing radiation (IR)-induced DSBs is non-homologous end joining (NHEJ). Here we discuss recent developments in our understanding of the mechanism of NHEJ, the...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Chen, Lees-Miller, Susan P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731128/
https://ncbi.nlm.nih.gov/pubmed/23433795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2013.01.011
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