Llwytho...
Overhang polarity of chromosomal double-strand breaks impacts kinetics and fidelity of yeast non-homologous end joining
Non-homologous end joining (NHEJ) is the main repair pathway for DNA double-strand breaks (DSBs) in cells with limited 5′ resection. To better understand how overhang polarity of chromosomal DSBs affects NHEJ, we made site-specific 5′-overhanging DSBs (5′ DSBs) in yeast using an optimized zinc finge...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Nucleic Acids Res |
|---|---|
| Prif Awduron: | , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Oxford University Press
2016
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4824102/ https://ncbi.nlm.nih.gov/pubmed/26773053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw013 |
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