載入...

XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair

DNA double strand breaks (DSBs), induced by ionizing radiation (IR) and endogenous stress including replication failure, are the most cytotoxic form of DNA damage. In human cells, most IR-induced DSBs are repaired by the non-homologous end joining (NHEJ) pathway. One of the most critical steps in NH...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Mahaney, Brandi L., Hammel, Michal, Meek, Katheryn, Tainer, John A., Lees-Miller, Susan P.
格式: Artigo
語言:Inglês
出版: 2013
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725335/
https://ncbi.nlm.nih.gov/pubmed/23442139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/bcb-2012-0058
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!