DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks

Nonhomologous end joining (NHEJ) is the major pathway for the repair of DNA double strand breaks (DSBs) in human cells. NHEJ requires the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs), Ku70, Ku80, XRCC4, DNA ligase IV and Artemis, as well as DNA polymerases μ and λ and polynucleot...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Yu, Yaping, Mahaney, Brandi L., Yano, Ken-Ichi, Ye, Ruiqiong, Fang, Shujuan, Douglas, Pauline, Chen, David J., Lees-Miller, Susan P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350819/
https://ncbi.nlm.nih.gov/pubmed/18644470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.06.015
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge