DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks

Nonhomologous end joining (NHEJ) is the major pathway for the repair of DNA double strand breaks (DSBs) in human cells. NHEJ requires the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs), Ku70, Ku80, XRCC4, DNA ligase IV and Artemis, as well as DNA polymerases μ and λ and polynucleot...

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Bibliografiske detaljer
Main Authors: Yu, Yaping, Mahaney, Brandi L., Yano, Ken-Ichi, Ye, Ruiqiong, Fang, Shujuan, Douglas, Pauline, Chen, David J., Lees-Miller, Susan P.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350819/
https://ncbi.nlm.nih.gov/pubmed/18644470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.06.015
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