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Ku recruits XLF to DNA double-strand breaks
XRCC4-like factor (XLF)—also known as Cernunnos—has recently been shown to be involved in non-homologous end-joining (NHEJ), which is the main pathway for the repair of DNA double-strand breaks (DSBs) in mammalian cells. XLF is likely to enhance NHEJ by stimulating XRCC4–ligase IV-mediated joining o...
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| Main Authors: | , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2246615/ https://ncbi.nlm.nih.gov/pubmed/18064046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401137 |
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