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Dynamic behavior of DNA topoisomerase IIβ in response to DNA double-strand breaks

DNA topoisomerase II (Topo II) is crucial for resolving topological problems of DNA and plays important roles in various cellular processes, such as replication, transcription, and chromosome segregation. Although DNA topology problems may also occur during DNA repair, the possible involvement of To...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Morotomi-Yano, Keiko, Saito, Shinta, Adachi, Noritaka, Yano, Ken-ichi
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037730/
https://ncbi.nlm.nih.gov/pubmed/29985428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28690-6
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