Autophosphorylation of DNA-PK(CS) regulates its dynamics at DNA double-strand breaks

The DNA-dependent protein kinase catalytic subunit (DNA-PK(CS)) plays an important role during the repair of DNA double-strand breaks (DSBs). It is recruited to DNA ends in the early stages of the nonhomologous end-joining (NHEJ) process, which mediates DSB repair. To study DNA-PK(CS) recruitment in...

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Detalhes bibliográficos
Main Authors: Uematsu, Naoya, Weterings, Eric, Yano, Ken-ichi, Morotomi-Yano, Keiko, Jakob, Burkhard, Taucher-Scholz, Gisela, Mari, Pierre-Olivier, van Gent, Dik C., Chen, Benjamin P.C., Chen, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064131/
https://ncbi.nlm.nih.gov/pubmed/17438073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200608077
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