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Differential Repair Protein Recruitment at Sites of Clustered and Isolated DNA Double-Strand Breaks Produced by High-Energy Heavy Ions

DNA double-strand break (DSB) repair is crucial to maintain genomic stability. The fidelity of the repair depends on the complexity of the lesion, with clustered DSBs being more difficult to repair than isolated breaks. Using live cell imaging of heavy ion tracks produced at a high-energy particle a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Jakob, Burkhard, Dubiak-Szepietowska, Monika, Janiel, Ellen, Schmidt, Alina, Durante, Marco, Taucher-Scholz, Gisela
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989695/
https://ncbi.nlm.nih.gov/pubmed/31996740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58084-6
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