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Live cell microscopy analysis of radiation-induced DNA double-strand break motion

We studied the spatiotemporal organization of DNA damage processing by live cell microscopy analysis in human cells. In unirradiated U2OS osteosarcoma and HeLa cancer cells, a fast confined and Brownian-like motion of DNA repair protein foci was observed, which was not altered by radiation. By analy...

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Detalhes bibliográficos
Main Authors: Jakob, B., Splinter, J., Durante, M., Taucher-Scholz, G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642473/
https://ncbi.nlm.nih.gov/pubmed/19221031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810987106
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