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ATM Alters the Otherwise Robust Chromatin Mobility at Sites of DNA Double-Strand Breaks (DSBs) in Human Cells

Ionizing radiation induces DNA double strand breaks (DSBs) which can lead to the formation of chromosome rearrangements through error prone repair. In mammalian cells the positional stability of chromatin contributes to the maintenance of genome integrity. DSBs exhibit only a small, submicron scale...

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Detalhes bibliográficos
Main Authors: Becker, Annabelle, Durante, Marco, Taucher-Scholz, Gisela, Jakob, Burkhard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961414/
https://ncbi.nlm.nih.gov/pubmed/24651490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092640
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