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DNA Double Strand Breaks and Chromosomal Translocations Induced by DNA Topoisomerase II
DNA double strand breaks (DSBs) are the most cytotoxic lesions of those occurring in the DNA and can lead to cell death or result in genome mutagenesis and chromosomal translocations. Although most of these rearrangements have detrimental effects for cellular survival, single events can provide clon...
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| Publicado no: | Front Mol Biosci |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6915882/ https://ncbi.nlm.nih.gov/pubmed/31921889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2019.00141 |
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