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DNA Double Strand Breaks and Chromosomal Translocations Induced by DNA Topoisomerase II

DNA double strand breaks (DSBs) are the most cytotoxic lesions of those occurring in the DNA and can lead to cell death or result in genome mutagenesis and chromosomal translocations. Although most of these rearrangements have detrimental effects for cellular survival, single events can provide clon...

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Bibliografiska uppgifter
I publikationen:Front Mol Biosci
Huvudupphovsman: Gómez-Herreros, Fernando
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915882/
https://ncbi.nlm.nih.gov/pubmed/31921889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2019.00141
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