Dynamics of double strand breaks and chromosomal translocations

Chromosomal translocations are a major cause of cancer. At the same time, the mechanisms that lead to specific chromosomal translocations that associate different gene regions remain largely unknown. Translocations are induced by double strand breaks (DSBs) in DNA. Here we review recent data on the...

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Bibliografiske detaljer
Udgivet i:Mol Cancer
Main Authors: Iarovaia, Olga V, Rubtsov, Mikhail, Ioudinkova, Elena, Tsfasman, Tatiana, Razin, Sergey V, Vassetzky, Yegor S
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289179/
https://ncbi.nlm.nih.gov/pubmed/25404525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-249
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