Dynamics of double strand breaks and chromosomal translocations

Chromosomal translocations are a major cause of cancer. At the same time, the mechanisms that lead to specific chromosomal translocations that associate different gene regions remain largely unknown. Translocations are induced by double strand breaks (DSBs) in DNA. Here we review recent data on the...

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Veröffentlicht in:Mol Cancer
Hauptverfasser: Iarovaia, Olga V, Rubtsov, Mikhail, Ioudinkova, Elena, Tsfasman, Tatiana, Razin, Sergey V, Vassetzky, Yegor S
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289179/
https://ncbi.nlm.nih.gov/pubmed/25404525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-249
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