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Dynamics of double strand breaks and chromosomal translocations

Chromosomal translocations are a major cause of cancer. At the same time, the mechanisms that lead to specific chromosomal translocations that associate different gene regions remain largely unknown. Translocations are induced by double strand breaks (DSBs) in DNA. Here we review recent data on the...

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Detalles Bibliográficos
Publicado en:Mol Cancer
Main Authors: Iarovaia, Olga V, Rubtsov, Mikhail, Ioudinkova, Elena, Tsfasman, Tatiana, Razin, Sergey V, Vassetzky, Yegor S
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289179/
https://ncbi.nlm.nih.gov/pubmed/25404525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-249
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