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Chromatin dynamics during repair of chromosomal DNA double-strand breaks
The integrity of a eukaryotic genome is often challenged by DNA double-strand breaks (DSBs). Even a single, unrepaired DSB can be a lethal event, or such unrepaired damage can result in chromosomal instability and loss of genetic information. Furthermore, defects in the pathways that respond to and...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872485/ https://ncbi.nlm.nih.gov/pubmed/20495614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi.09.22 |
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