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A Rad51 Presynaptic Filament Is Sufficient to Capture Nucleosomal Homology during Recombinational Repair of a DNA Double-Strand Break

Repair of chromosomal DNA double-strand breaks by homologous recombination is essential for cell survival and genome stability. Within eukaryotic cells, this repair pathway requires a search for a homologous donor sequence and a subsequent strand invasion event on chromatin fibers. We employ a bioti...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Sinha, Manisha, Peterson, Craig L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461863/
https://ncbi.nlm.nih.gov/pubmed/18570881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.04.015
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