GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination

RAD51 is a key factor in homologous recombination (HR) and plays an essential role in cellular proliferation by repairing DNA damage during replication. The assembly of RAD51 at DNA damage is strictly controlled by RAD51 mediators, including BRCA1 and BRCA2. We found that human RAD51 directly binds...

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Detalhes bibliográficos
Main Authors: Takizawa, Yoshimasa, Qing, Yong, Takaku, Motoki, Ishida, Takako, Morozumi, Yuichi, Tsujita, Takashi, Kogame, Toshiaki, Hirota, Kouji, Takahashi, Masayuki, Shibata, Takehiko, Kurumizaka, Hitoshi, Takeda, Shunichi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926616/
https://ncbi.nlm.nih.gov/pubmed/20403813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq271
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