GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination

RAD51 is a key factor in homologous recombination (HR) and plays an essential role in cellular proliferation by repairing DNA damage during replication. The assembly of RAD51 at DNA damage is strictly controlled by RAD51 mediators, including BRCA1 and BRCA2. We found that human RAD51 directly binds...

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Bibliographische Detailangaben
Hauptverfasser: Takizawa, Yoshimasa, Qing, Yong, Takaku, Motoki, Ishida, Takako, Morozumi, Yuichi, Tsujita, Takashi, Kogame, Toshiaki, Hirota, Kouji, Takahashi, Masayuki, Shibata, Takehiko, Kurumizaka, Hitoshi, Takeda, Shunichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2010
Schlagworte:
Genome Integrity, Repair and Replication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926616/
https://ncbi.nlm.nih.gov/pubmed/20403813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq271
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