GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination

RAD51 is a key factor in homologous recombination (HR) and plays an essential role in cellular proliferation by repairing DNA damage during replication. The assembly of RAD51 at DNA damage is strictly controlled by RAD51 mediators, including BRCA1 and BRCA2. We found that human RAD51 directly binds...

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Bibliographic Details
Main Authors: Takizawa, Yoshimasa, Qing, Yong, Takaku, Motoki, Ishida, Takako, Morozumi, Yuichi, Tsujita, Takashi, Kogame, Toshiaki, Hirota, Kouji, Takahashi, Masayuki, Shibata, Takehiko, Kurumizaka, Hitoshi, Takeda, Shunichi
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
Subjects:
Genome Integrity, Repair and Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926616/
https://ncbi.nlm.nih.gov/pubmed/20403813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq271
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