DIDS, a chemical compound that inhibits RAD51-mediated homologous pairing and strand exchange

RAD51, an essential eukaryotic DNA recombinase, promotes homologous pairing and strand exchange during homologous recombination and the recombinational repair of double strand breaks. Mutations that up- or down-regulate RAD51 gene expression have been identified in several tumors, suggesting that in...

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Библиографические подробности
Главные авторы: Ishida, Takako, Takizawa, Yoshimasa, Kainuma, Takashi, Inoue, Jin, Mikawa, Tsutomu, Shibata, Takehiko, Suzuki, Hidekazu, Tashiro, Satoshi, Kurumizaka, Hitoshi
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2009
Предметы:
Genome Integrity, Repair and Replication
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691838/
https://ncbi.nlm.nih.gov/pubmed/19336413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp200
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