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DIDS, a chemical compound that inhibits RAD51-mediated homologous pairing and strand exchange
RAD51, an essential eukaryotic DNA recombinase, promotes homologous pairing and strand exchange during homologous recombination and the recombinational repair of double strand breaks. Mutations that up- or down-regulate RAD51 gene expression have been identified in several tumors, suggesting that in...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
2009
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2691838/ https://ncbi.nlm.nih.gov/pubmed/19336413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp200 |
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