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Human PSF binds to RAD51 and modulates its homologous-pairing and strand-exchange activities

RAD51, a eukaryotic recombinase, catalyzes homologous-pairing and strand-exchange reactions, which are essential steps in homologous recombination and recombinational repair of double strand breaks. On the other hand, human PSF was originally identified as a component of spliceosomes, and its multip...

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Detalhes bibliográficos
Main Authors: Morozumi, Yuichi, Takizawa, Yoshimasa, Takaku, Motoki, Kurumizaka, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715225/
https://ncbi.nlm.nih.gov/pubmed/19447914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp298
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