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Chromatin dynamics and the repair of DNA double strand breaks

DNA double-strand breaks (DSBs) arise through both replication errors and from exogenous events such as exposure to ionizing radiation. DSBs are potentially lethal, and cells have evolved a highly conserved mechanism to detect and repair these lesions. This mechanism involves phosphorylation of hist...

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Détails bibliographiques
Auteurs principaux: Xu, Ye, Price, Brendan D
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048797/
https://ncbi.nlm.nih.gov/pubmed/21212734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.2.14543
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