Enhanced Antigen Retrieval of Amyloid β Immunohistochemistry: Re-evaluation of Amyloid β Pathology in Alzheimer Disease and Its Mouse Model

by Kai, Hideaki, Shin, Ryong-Woon, Ogino, Koichi, Hatsuta, Hiroyuki, Murayama, Shigeo, Kitamoto, Tetsuyuki
Published 2012

Alpha-synuclein immunohistochemistry of gastrointestinal and biliary surgical specimens for diagnosis of Lewy body disease

by Ito, Shinji, Takao, Masaki, Hatsuta, Hiroyuki, Kanemaru, Kazutomi, Arai, Tomio, Saito, Yuko, Fukayama, Masashi, Murayama, Shigeo
Published 2014

Optineurin pathology in the spinal cord of amyotrophic lateral sclerosis/parkinsonism‐dementia complex patients in Kii Peninsula, Japan

by Morimoto, Satoru, Hatsuta, Hiroyuki, Motoyama, Rie, Kokubo, Yasumasa, Ishiura, Hiroyuki, Tsuji, Shoji, Kuzuhara, Shigeki, Murayama, Shigeo
Published in Brain Pathol (2018)

Imbalance in Fatty-Acid-Chain Length of Gangliosides Triggers Alzheimer Amyloid Deposition in the Precuneus

by Oikawa, Naoto, Matsubara, Teruhiko, Fukuda, Ryoto, Yasumori, Hanaki, Hatsuta, Hiroyuki, Murayama, Shigeo, Sato, Toshinori, Suzuki, Akemi, Yanagisawa, Katsuhiko
Published in PLoS One (2015)

Serum microRNA miR-501-3p as a potential biomarker related to the progression of Alzheimer’s disease

by Hara, Norikazu, Kikuchi, Masataka, Miyashita, Akinori, Hatsuta, Hiroyuki, Saito, Yuko, Kasuga, Kensaku, Murayama, Shigeo, Ikeuchi, Takeshi, Kuwano, Ryozo
Published in Acta Neuropathol Commun (2017)

The Homologous Carboxyl-Terminal Domains of Microtubule-Associated Protein 2 and TAU Induce Neuronal Dysfunction and Have Differential Fates in the Evolution of Neurofibrillary Tan...

by Xie, Ce, Miyasaka, Tomohiro, Yoshimura, Satomi, Hatsuta, Hiroyuki, Yoshina, Sawako, Kage-Nakadai, Eriko, Mitani, Shohei, Murayama, Shigeo, Ihara, Yasuo
Published 2014

Incidence and extent of TDP-43 accumulation in aging human brain

by Uchino, Akiko, Takao, Masaki, Hatsuta, Hiroyuki, Sumikura, Hiroyuki, Nakano, Yuta, Nogami, Akane, Saito, Yuko, Arai, Tomio, Nishiyama, Kazutoshi, Murayama, Shigeo
Published in Acta Neuropathol Commun (2015)

Distribution of α-synuclein in the spinal cord and dorsal root ganglia in an autopsy cohort of elderly persons

by Sumikura, Hiroyuki, Takao, Masaki, Hatsuta, Hiroyuki, Ito, Shinji, Nakano, Yuta, Uchino, Akiko, Nogami, Akane, Saito, Yuko, Mochizuki, Hideki, Murayama, Shigeo
Published in Acta Neuropathol Commun (2015)

Unusual tau pathology of the cerebellum in patients with amyotrophic lateral sclerosis/parkinsonism–dementia complex from the Kii Peninsula, Japan

by Morimoto, Satoru, Hatsuta, Hiroyuki, Kokubo, Yasumasa, Nakano, Yuta, Hasegawa, Masato, Yoneda, Misao, Hirokawa, Yoshifumi, Kuzuhara, Shigeki, Shiraishi, Taizo, Murayama, Shigeo
Published in Brain Pathol (2018)

Monoclonal Antibody Against the Turn of the 42-Residue Amyloid β-Protein at Positions 22 and 23

by Murakami, Kazuma, Horikoshi-Sakuraba, Yuko, Murata, Nakaba, Noda, Yoshihiro, Masuda, Yuichi, Kinoshita, Noriaki, Hatsuta, Hiroyuki, Murayama, Shigeo, Shirasawa, Takuji, Shimizu, Takahiko, Irie, Kazuhiro
Published 2010

Spliceosome integrity is defective in the motor neuron diseases ALS and SMA

by Tsuiji, Hitomi, Iguchi, Yohei, Furuya, Asako, Kataoka, Ayane, Hatsuta, Hiroyuki, Atsuta, Naoki, Tanaka, Fumiaki, Hashizume, Yoshio, Akatsu, Hiroyasu, Murayama, Shigeo, Sobue, Gen, Yamanaka, Koji
Published 2013

Homovanillic acid and 5-hydroxyindole acetic acid as biomarkers for dementia with Lewy bodies and coincident Alzheimer’s disease: An autopsy-confirmed study

by Morimoto, Satoru, Takao, Masaki, Hatsuta, Hiroyuki, Nishina, Yasushi, Komiya, Tadashi, Sengoku, Renpei, Nakano, Yuta, Uchino, Akiko, Sumikura, Hiroyuki, Saito, Yuko, Kanemaru, Kazutomi, Murayama, Shigeo
Published in PLoS One (2017)

Tau and TDP-43 accumulation of the basal nucleus of Meynert in individuals with cerebral lobar infarcts or hemorrhage

by Hatsuta, Hiroyuki, Takao, Masaki, Nogami, Akane, Uchino, Akiko, Sumikura, Hiroyuki, Takata, Tadayuki, Morimoto, Satoru, Kanemaru, Kazutomi, Adachi, Tadashi, Arai, Tomio, Hasegawa, Masato, Murayama, Shigeo
Published in Acta Neuropathol Commun (2019)

SOD1 (Copper/Zinc Superoxide Dismutase) Deficiency Drives Amyloid β Protein Oligomerization and Memory Loss in Mouse Model of Alzheimer Disease

by Murakami, Kazuma, Murata, Nakaba, Noda, Yoshihiro, Tahara, Shoichi, Kaneko, Takao, Kinoshita, Noriaki, Hatsuta, Hiroyuki, Murayama, Shigeo, Barnham, Kevin J., Irie, Kazuhiro, Shirasawa, Takuji, Shimizu, Takahiko
Published 2011

Extensive deamidation at asparagine residue 279 accounts for weak immunoreactivity of tau with RD4 antibody in Alzheimer’s disease brain

by Dan, Ayaho, Takahashi, Muneaki, Masuda-Suzukake, Masami, Kametani, Fuyuki, Nonaka, Takashi, Kondo, Hiromi, Akiyama, Haruhiko, Arai, Takao, Mann, David MA, Saito, Yuko, Hatsuta, Hiroyuki, Murayama, Shigeo, Hasegawa, Masato
Published 2013

Imaging spectrum of sporadic cerebral amyloid angiopathy: multifaceted features of a single pathological condition

by Sakurai, Keita, Tokumaru, Aya M., Nakatsuka, Tomoya, Murayama, Shigeo, Hasebe, Shin, Imabayashi, Etsuko, Kanemaru, Kazutomi, Takao, Masaki, Hatsuta, Hiroyuki, Ishii, Kenji, Saito, Yuko, Shibamoto, Yuta, Matsukawa, Noriyuki, Chikui, Emiko, Terada, Hitoshi
Published 2014

An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease

by Kizuka, Yasuhiko, Kitazume, Shinobu, Fujinawa, Reiko, Saito, Takashi, Iwata, Nobuhisa, Saido, Takaomi C, Nakano, Miyako, Yamaguchi, Yoshiki, Hashimoto, Yasuhiro, Staufenbiel, Matthias, Hatsuta, Hiroyuki, Murayama, Shigeo, Manya, Hiroshi, Endo, Tamao, Taniguchi, Naoyuki
Published in EMBO Mol Med (2015)

Immunostaining of Oxidized DJ-1 in Human and Mouse Brains

by Saito, Yoshiro, Miyasaka, Tomohiro, Hatsuta, Hiroyuki, Takahashi-Niki, Kazuko, Hayashi, Kojiro, Mita, Yuichiro, Kusano-Arai, Osamu, Iwanari, Hiroko, Ariga, Hiroyoshi, Hamakubo, Takao, Yoshida, Yasukazu, Niki, Etsuo, Murayama, Shigeo, Ihara, Yasuo, Noguchi, Noriko
Published 2014

Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease

by Kakuda, Nobuto, Shoji, Mikio, Arai, Hiroyuki, Furukawa, Katsutoshi, Ikeuchi, Takeshi, Akazawa, Kohei, Takami, Mako, Hatsuta, Hiroyuki, Murayama, Shigeo, Hashimoto, Yasuhiro, Miyajima, Masakazu, Arai, Hajime, Nagashima, Yu, Yamaguchi, Haruyasu, Kuwano, Ryozo, Nagaike, Kazuhiro, Ihara, Yasuo
Published 2012

Age-Dependent Relationship Between Plasma Aβ40 and Aβ42 and Total Tau Levels in Cognitively Normal Subjects

by Lue, Lih-Fen, Pai, Ming-Chyi, Chen, Ta-Fu, Hu, Chaur-Jong, Huang, Li-Kai, Lin, Wei-Che, Wu, Chau-Chung, Jeng, Jian-Shing, Blennow, Kaj, Sabbagh, Marwan N., Yan, Sui-Hing, Wang, Pei-Ning, Yang, Shieh-Yueh, Hatsuta, Hiroyuki, Morimoto, Satoru, Takeda, Akitoshi, Itoh, Yoshiaki, Liu, Jun, Xie, Haiqun, Chiu, Ming-Jang
Published in Front Aging Neurosci (2019)