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Incidence and extent of TDP-43 accumulation in aging human brain
INTRODUCTION: The transactivation response element DNA-binding protein 43 kDa (TDP-43) is a major component of the ubiquitin-positive and tau-negative inclusions in frontotemporal lobar degeneration and sporadic amyotrophic lateral sclerosis (ALS). TDP-43 may accumulate in cases of Alzheimer’s disea...
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| Publicado no: | Acta Neuropathol Commun |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4473839/ https://ncbi.nlm.nih.gov/pubmed/26091809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0215-1 |
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