Mass spectrometric analysis of accumulated TDP-43 in amyotrophic lateral sclerosis brains

TDP-43 is the major disease-associated protein involved in the pathogenesis and progression of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with ubiquitin-positive inclusions linked to TDP-43 pathology (FTLD-TDP). Abnormal phosphorylation, truncation and cytoplasmic mis-...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Kametani, Fuyuki, Obi, Tomokazu, Shishido, Takeo, Akatsu, Hiroyasu, Murayama, Shigeo, Saito, Yuko, Yoshida, Mari, Hasegawa, Masato
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793195/
https://ncbi.nlm.nih.gov/pubmed/26980269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23281
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