α-Synuclein as CSF and Blood Biomarker of Dementia with Lewy Bodies

Por Kasuga, Kensaku, Nishizawa, Masatoyo, Ikeuchi, Takeshi
Publicado em 2012

A Patient with Fragile X-Associated Tremor/Ataxia Syndrome Presenting with Executive Cognitive Deficits and Cerebral White Matter Lesions

Por Kasuga, Kensaku, Ikeuchi, Takeshi, Arakawa, Keiko, Yajima, Ryuji, Tokutake, Takayoshi, Nishizawa, Masatoyo
Publicado em 2011

Hyperphosphorylation of Tau Induced by Naturally Secreted Amyloid-β at Nanomolar Concentrations Is Modulated by Insulin-dependent Akt-GSK3β Signaling Pathway

Por Tokutake, Takayoshi, Kasuga, Kensaku, Yajima, Ryuji, Sekine, Yumi, Tezuka, Toshiyuki, Nishizawa, Masatoyo, Ikeuchi, Takeshi
Publicado em 2012

Extensive aggregation of α-synuclein and tau in juvenile-onset neuroaxonal dystrophy: an autopsied individual with a novel mutation in the PLA2G6 gene-splicing site

Por Riku, Yuichi, Ikeuchi, Takeshi, Yoshino, Hiroyo, Mimuro, Maya, Mano, Kazuo, Goto, Yoji, Hattori, Nobutaka, Sobue, Gen, Yoshida, Mari
Publicado em 2013

Serum microRNA miR-501-3p as a potential biomarker related to the progression of Alzheimer’s disease

Por Hara, Norikazu, Kikuchi, Masataka, Miyashita, Akinori, Hatsuta, Hiroyuki, Saito, Yuko, Kasuga, Kensaku, Murayama, Shigeo, Ikeuchi, Takeshi, Kuwano, Ryozo
Publicado no Acta Neuropathol Commun (2017)

Systematic review and meta-analysis of Japanese familial Alzheimer's disease and FTDP-17

Por Kasuga, Kensaku, Kikuchi, Masataka, Tokutake, Takayoshi, Nakaya, Akihiro, Tezuka, Toshiyuki, Tsukie, Tamao, Hara, Norikazu, Miyashita, Akinori, Kuwano, Ryozo, Ikeuchi, Takeshi
Publicado no J Hum Genet (2015)

Reduced plasma desmosterol-to-cholesterol ratio and longitudinal cognitive decline in Alzheimer's disease

Por Sato, Yoshiaki, Bernier, Francois, Yamanaka, Yasukazu, Aoshima, Ken, Oda, Yoshiya, Ingelsson, Martin, Lannfelt, Lars, Miyashita, Akinori, Kuwano, Ryozo, Ikeuchi, Takeshi
Publicado no Alzheimers Dement (Amst) (2015)

Reduced CSF Water Influx in Alzheimer’s Disease Supporting the β-Amyloid Clearance Hypothesis

Por Suzuki, Yuji, Nakamura, Yukihiro, Yamada, Kenichi, Igarashi, Hironaka, Kasuga, Kensaku, Yokoyama, Yuichi, Ikeuchi, Takeshi, Nishizawa, Masatoyo, Kwee, Ingrid L., Nakada, Tsutomu
Publicado no PLoS One (2015)

Elevated C-Reactive Protein Is Associated with Cognitive Decline in Outpatients of a General Hospital: The Project in Sado for Total Health (PROST)

Por Watanabe, Yumi, Kitamura, Kaori, Nakamura, Kazutoshi, Sanpei, Kazuhiro, Wakasugi, Minako, Yokoseki, Akio, Onodera, Osamu, Ikeuchi, Takeshi, Kuwano, Ryozo, Momotsu, Takeshi, Narita, Ichiei, Endo, Naoto
Publicado no Dement Geriatr Cogn Dis Extra (2016)

Modifiable Factors Associated with Cognitive Impairment in 1,143 Japanese Outpatients: The Project in Sado for Total Health (PROST)

Por Kitamura, Kaori, Watanabe, Yumi, Nakamura, Kazutoshi, Sanpei, Kazuhiro, Wakasugi, Minako, Yokoseki, Akio, Onodera, Osamu, Ikeuchi, Takeshi, Kuwano, Ryozo, Momotsu, Takeshi, Narita, Ichiei, Endo, Naoto
Publicado no Dement Geriatr Cogn Dis Extra (2016)

Evidence for a Common Founder and Clinical Characteristics of Japanese Families with the MAPT R406W Mutation

Por Ikeuchi, Takeshi, Imamura, Toru, Kawase, Yasuhiro, Kitade, Yoshimi, Tsuchiya, Miyuki, Tokutake, Takayoshi, Kasuga, Kensaku, Yajima, Ryuji, Tsukie, Tamao, Miyashita, Akinori, Sugishita, Morihiro, Kuwano, Ryozo, Nishizawa, Masatoyo
Publicado em 2011

Coordinated increase of γ-secretase reaction products in the plasma of some female Japanese sporadic Alzheimer's disease patients: quantitative analysis of p3-Alcα with a new ELISA...

Por Konno, Tomoko, Hata, Saori, Hamada, Yukiko, Horikoshi-Sakuraba, Yuko, Nakaya, Tadashi, Saito, Yuhki, Yamamoto, Tohru, Yamamoto, Takayuki, Maeda, Masahiro, Ikeuchi, Takeshi, Gandy, Sam, Akatsu, Hiroyasu, Suzuki, Toshiharu
Publicado em 2011

Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of γ-secretase using synthetic antibodies

Por Zhang, Xulun, Hoey, Robert J., Lin, Guoqing, Koide, Akiko, Leung, Brenda, Ahn, Kwangwook, Dolios, Georgia, Paduch, Marcin, Ikeuchi, Takeshi, Wang, Rong, Li, Yue-Ming, Koide, Shohei, Sisodia, Sangram S.
Publicado em 2012

Multiple γ-secretase product peptides are coordinately increased in concentration in the cerebrospinal fluid of a subpopulation of sporadic Alzheimer’s disease subjects

Por Hata, Saori, Taniguchi, Miyako, Piao, Yi, Ikeuchi, Takeshi, Fagan, Anne M, Holtzman, David M, Bateman, Randall, Sohrabi, Hamid R, Martins, Ralph N, Gandy, Sam, Urakami, Katsuya, Suzuki, Toshiharu
Publicado em 2012

Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease

Por Kakuda, Nobuto, Shoji, Mikio, Arai, Hiroyuki, Furukawa, Katsutoshi, Ikeuchi, Takeshi, Akazawa, Kohei, Takami, Mako, Hatsuta, Hiroyuki, Murayama, Shigeo, Hashimoto, Yasuhiro, Miyajima, Masakazu, Arai, Hajime, Nagashima, Yu, Yamaguchi, Haruyasu, Kuwano, Ryozo, Nagaike, Kazuhiro, Ihara, Yasuo
Publicado em 2012

Haploinsufficiency of CSF-1R and clinicopathologic characterization in patients with HDLS

Por Konno, Takuya, Tada, Masayoshi, Tada, Mari, Koyama, Akihide, Nozaki, Hiroaki, Harigaya, Yasuo, Nishimiya, Jin, Matsunaga, Akiko, Yoshikura, Nobuaki, Ishihara, Kenji, Arakawa, Musashi, Isami, Aiko, Okazaki, Kenichi, Yokoo, Hideaki, Itoh, Kyoko, Yoneda, Makoto, Kawamura, Mitsuru, Inuzuka, Takashi, Takahashi, Hitoshi, Nishizawa, Masatoyo, Onodera, Osamu, Kakita, Akiyoshi, Ikeuchi, Takeshi
Publicado em 2014

The 28-amino acid form of an APLP1-derived Aβ-like peptide is a surrogate marker for Aβ42 production in the central nervous system

Por Yanagida, Kanta, Okochi, Masayasu, Tagami, Shinji, Nakayama, Taisuke, Kodama, Takashi S, Nishitomi, Kouhei, Jiang, Jingwei, Mori, Kohji, Tatsumi, Shin-ichi, Arai, Tetsuaki, Ikeuchi, Takeshi, Kasuga, Kensaku, Tokuda, Takahiko, Kondo, Masaki, Ikeda, Masaki, Deguchi, Kentaro, Kazui, Hiroaki, Tanaka, Toshihisa, Morihara, Takashi, Hashimoto, Ryota, Kudo, Takashi, Steiner, Harald, Haass, Christian, Tsuchiya, Kuniaki, Akiyama, Haruhiko, Kuwano, Ryozo, Takeda, Masatoshi
Publicado em 2009

SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians

Por Miyashita, Akinori, Koike, Asako, Jun, Gyungah, Wang, Li-San, Takahashi, Satoshi, Matsubara, Etsuro, Kawarabayashi, Takeshi, Shoji, Mikio, Tomita, Naoki, Arai, Hiroyuki, Asada, Takashi, Harigaya, Yasuo, Ikeda, Masaki, Amari, Masakuni, Hanyu, Haruo, Higuchi, Susumu, Ikeuchi, Takeshi, Nishizawa, Masatoyo, Suga, Masaichi, Kawase, Yasuhiro, Akatsu, Hiroyasu, Kosaka, Kenji, Yamamoto, Takayuki, Imagawa, Masaki, Hamaguchi, Tsuyoshi, Yamada, Masahito, Moriaha, Takashi, Takeda, Masatoshi, Takao, Takeo, Nakata, Kenji, Fujisawa, Yoshikatsu, Sasaki, Ken, Watanabe, Ken, Nakashima, Kenji, Urakami, Katsuya, Ooya, Terumi, Takahashi, Mitsuo, Yuzuriha, Takefumi, Serikawa, Kayoko, Yoshimoto, Seishi, Nakagawa, Ryuji, Kim, Jong-Won, Ki, Chang-Seok, Won, Hong-Hee, Na, Duk L., Seo, Sang Won, Mook-Jung, Inhee, St. George-Hyslop, Peter, Mayeux, Richard, Haines, Jonathan L., Pericak-Vance, Margaret A., Yoshida, Makiko, Nishida, Nao, Tokunaga, Katsushi, Yamamoto, Ken, Tsuji, Shoji, Kanazawa, Ichiro, Ihara, Yasuo, Schellenberg, Gerard D., Farrer, Lindsay A., Kuwano, Ryozo
Publicado em 2013

Correction: SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians

Por Miyashita, Akinori, Koike, Asako, Jun, Gyungah, Wang, Li-San, Takahashi, Satoshi, Matsubara, Etsuro, Kawarabayashi, Takeshi, Shoji, Mikio, Tomita, Naoki, Arai, Hiroyuki, Asada, Takashi, Harigaya, Yasuo, Ikeda, Masaki, Amari, Masakuni, Hanyu, Haruo, Higuchi, Susumu, Ikeuchi, Takeshi, Nishizawa, Masatoyo, Suga, Masaichi, Kawase, Yasuhiro, Akatsu, Hiroyasu, Kosaka, Kenji, Yamamoto, Takayuki, Imagawa, Masaki, Hamaguchi, Tsuyoshi, Yamada, Masahito, Morihara, Takashi, Takeda, Masatoshi, Takao, Takeo, Nakata, Kenji, Fujisawa, Yoshikatsu, Sasaki, Ken, Watanabe, Ken, Nakashima, Kenji, Urakami, Katsuya, Ooya, Terumi, Takahashi, Mitsuo, Yuzuriha, Takefumi, Serikawa, Kayoko, Yoshimoto, Seishi, Nakagawa, Ryuji, Kim, Jong-Won, Ki, Chang-Seok, Won, Hong-Hee, Na, Duk L., Seo, Sang Won, Mook-Jung, Inhee, St. George-Hyslop, Peter, Mayeux, Richard, Haines, Jonathan L., Pericak-Vance, Margaret A., Yoshida, Makiko, Nishida, Nao, Tokunaga, Katsushi, Yamamoto, Ken, Tsuji, Shoji, Kanazawa, Ichiro, Ihara, Yasuo, Schellenberg, Gerard D., Farrer, Lindsay A., Kuwano, Ryozo
Publicado em 2013