The effect of the catalytic topoisomerase II inhibitor dexrazoxane (ICRF-187) on CC9C10 hybridoma viability and productivity

por Barnabé, Norman, Butler, Michael, Hasinoff, Brian B.
Publicado 2001

Cadmium is a Catalytic Inhibitor of DNA Topoisomerase II

por Wu, Xing, Yalowich, Jack C., Hasinoff, Brian B.
Publicado 2011

Production of nitric oxide and reactions with plant hemoglobins under hypoxic stress

por Dordas, Christos, Hasinoff, Brian B, Rivoal, Jean, Hill, Robert D
Publicado 2005

Design, synthesis and biological evaluation of a novel series of bisintercalating DNA-binding piperazine-linked bisanthrapyrazole compounds as anticancer agents

por Zhang, Rui, Wu, Xing, Yalowich, Jack C., Hasinoff, Brian B.
Publicado 2011

A diazirine-based photoaffinity etoposide probe for labeling topoisomerase II

por Chee, Gaik-Lean, Yalowich, Jack C., Bodner, Andrew, Wu, Xing, Hasinoff, Brian B.
Publicado 2009

The anticancer multi-kinase inhibitor dovitinib also targets topoisomerase I and topoisomerase II

por Hasinoff, Brian B., Wu, Xing, Nitiss, John L., Kanagasabai, Ragu, Yalowich, Jack C.
Publicado 2012

Structure-based design, synthesis and biological testing of etoposide analog epipodophyllotoxin-N-mustard hybrid compounds designed to covalently bind to topoisomerase II and DNA

por Yadav, Arun A., Wu, Xing, Patel, Daywin, Yalowich, Jack C., Hasinoff, Brian B.
Publicado en Bioorg Med Chem (2014)

Evaluation of Nitrobenzyl Derivatives of Camptothecin as Anti-Cancer Agents and Potential Hypoxia Targeting Prodrugs

por Liang, Dinghua, Wu, Xing, Hasinoff, Brian B., Herbert, David E., Tranmer, Geoffrey K.
Publicado en Molecules (2018)

The anticancer thiosemicarbazones Dp44mT and triapine lack inhibitory effects as catalytic inhibitors or poisons of DNA topoisomerase IIα

por Yalowich, Jack C., Wu, Xing, Zhang, Rui, Kanagasabai, Ragu, Hornbaker, Marissa, Hasinoff, Brian B.
Publicado 2012

Mechanisms of Action and Reduced Cardiotoxicity of Pixantrone; a Topoisomerase II Targeting Agent with Cellular Selectivity for the Topoisomerase IIα Isoform

por Hasinoff, Brian B., Wu, Xing, Patel, Daywin, Kanagasabai, Ragu, Karmahapatra, Soumendrakrishna, Yalowich, Jack C.
Publicado en J Pharmacol Exp Ther (2016)

Structure-based design, synthesis and biological testing of piperazine-linked bis-epipodophyllotoxin etoposide analogs

por Yadav, Arun A., Chee, Gaik-Lean, Wu, Xing, Patel, Daywin, Yalowich, Jack C., Hasinoff, Brian B.
Publicado en Bioorg Med Chem (2015)

The structure-based design, synthesis and biological evaluation of DNA-binding bisintercalating bisanthrapyrazole anticancer compounds

por Hasinoff, Brian B., Liang, Hong, Wu, Xing, Guziec, Lynn J., Guziec, Frank S., Marshall, Kyle, Yalowich, Jack C.
Publicado 2008

Design, synthesis and biological evaluation of a novel series of anthrapyrazoles linked with netropsin-like oligopyrrole carboxamides as anticancer agents

por Zhang, Rui, Wu, Xing, Guziec, Lynn J., Guziec, Frank S., Chee, Gaik-Lean, Yalowich, Jack C., Hasinoff, Brian B.
Publicado 2010

Mechanism of the cytotoxicity of the diazoparaquinone antitumor antibiotic kinamycin F

por O’Hara, Kimberley A., Wu, Xing, Patel, Daywin, Liang, Hong, Yalowich, Jack C., Chen, Nan, Goodfellow, Valery, Adedayo, Otunola, Dmitrienko, Gary I., Hasinoff, Brian B.
Publicado 2007

Arrest of B16 Melanoma Cells in the Mouse Pulmonary Microcirculation Induces Endothelial Nitric Oxide Synthase-Dependent Nitric Oxide Release that Is Cytotoxic to the Tumor Cells

por Qiu, Hongming, Orr, F.William, Jensen, Derrek, Wang, Hui Helen, McIntosh, Alan R., Hasinoff, Brian B., Nance, Dwight M., Pylypas, Susan, Qi, Ke, Song, Chun, Muschel, Ruth J., Al-Mehdi, Abu-Bakr
Publicado 2003