Forced Expression of Heat Shock Protein 27 (Hsp27) Reverses P-Glycoprotein (ABCB1)-mediated Drug Efflux and MDR1 Gene Expression in Adriamycin-resistant Human Breast Cancer Cells

Por Kanagasabai, Ragu, Krishnamurthy, Karthikeyan, Druhan, Lawrence J., Ilangovan, Govindasamy
Publicado em 2011

Heat Shock Protein 25-Enriched Plasma Transfusion Preconditions the Heart against Doxorubicin-Induced Dilated Cardiomyopathy in Mice

Por Krishnamurthy, Karthikeyan, Kanagasabai, Ragu, Druhan, Lawrence J., Ilangovan, Govindasamy
Publicado em 2012

Heat shock factor-1 knockout induces multidrug resistance gene, MDR1b, and enhances P-glycoprotein (ABCB1)-based drug extrusion in the heart

Por Krishnamurthy, Karthikeyan, Vedam, Kaushik, Kanagasabai, Ragu, Druhan, Lawrence J., Ilangovan, Govindasamy
Publicado em 2012

Hsp27 Protects Adenocarcinoma Cells from UV-induced Apoptosis by Akt and p21 Dependent Pathway of Survival

Por Kanagasabai, Ragu, Krishnamurthy, Karthikeyan, Vedam, Kaushik, Wang, Qien, Zhu, Qianzheng, Ilangovan, Govindasamy
Publicado em 2010

The anticancer multi-kinase inhibitor dovitinib also targets topoisomerase I and topoisomerase II

Por Hasinoff, Brian B., Wu, Xing, Nitiss, John L., Kanagasabai, Ragu, Yalowich, Jack C.
Publicado em 2012

The anticancer thiosemicarbazones Dp44mT and triapine lack inhibitory effects as catalytic inhibitors or poisons of DNA topoisomerase IIα

Por Yalowich, Jack C., Wu, Xing, Zhang, Rui, Kanagasabai, Ragu, Hornbaker, Marissa, Hasinoff, Brian B.
Publicado em 2012

Mechanisms of Action and Reduced Cardiotoxicity of Pixantrone; a Topoisomerase II Targeting Agent with Cellular Selectivity for the Topoisomerase IIα Isoform

Por Hasinoff, Brian B., Wu, Xing, Patel, Daywin, Kanagasabai, Ragu, Karmahapatra, Soumendrakrishna, Yalowich, Jack C.
Publicado no J Pharmacol Exp Ther (2016)

Ubiquitin-family modifications of topoisomerase I in camptothecin-treated human breast cancer cells

Por Kanagasabai, Ragu, Liu, Shujun, Salama, Samir, Yamasaki, Edith F., Zhang, Liwen, Greenchurch, Kari B., Snapka, Robert M.
Publicado em 2009

TRIM72 modulates caveolar endocytosis in repair of lung cells

Por Nagre, Nagaraja, Wang, Shaohua, Kellett, Thomas, Kanagasabai, Ragu, Deng, Jing, Nishi, Miyuki, Shilo, Konstantin, Oeckler, Richard A., Yalowich, Jack C., Takeshima, Hiroshi, Christman, John, Hubmayr, Rolf D., Zhao, Xiaoli
Publicado no Am J Physiol Lung Cell Mol Physiol (2015)

Cytotoxic and natural killer cell stimulatory constituents of Phyllanthus songboiensis

Por Ren, Yulin, Yuan, Chunhua, Deng, Youcai, Kanagasabai, Ragu, Ninh, Tran Ngoc, Tu, Vuong Tan, Chai, Hee-Byung, Soejarto, Djaja D., Fuchs, James R., Yalowich, Jack C., Yu, Jianhua, Kinghorn, A. Douglas
Publicado no Phytochemistry (2015)

Potent Cytotoxic Arylnaphthalene Lignan Lactones from Phyllanthus poilanei

Por Ren, Yulin, Lantvit, Daniel D., Deng, Youcai, Kanagasabai, Ragu, Gallucci, Judith C., Ninh, Tran Ngoc, Chai, Hee-Byung, Soejarto, Djaja D., Fuchs, James R., Yalowich, Jack C., Yu, Jianhua, Swanson, Steven M., Kinghorn, A. Douglas
Publicado em 2014