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Design, synthesis and biological evaluation of a novel series of anthrapyrazoles linked with netropsin-like oligopyrrole carboxamides as anticancer agents

Anticancer drugs that bind to DNA and inhibit DNA-processing enzymes represent an important class of anticancer drugs. Combilexin molecules, which combine DNA minor groove binding and intercalating functionalities, have the potential for increased DNA binding affinity and increased selectivity due t...

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Detalhes bibliográficos
Main Authors: Zhang, Rui, Wu, Xing, Guziec, Lynn J., Guziec, Frank S., Chee, Gaik-Lean, Yalowich, Jack C., Hasinoff, Brian B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880227/
https://ncbi.nlm.nih.gov/pubmed/20471276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.04.028
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