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Cadmium is a Catalytic Inhibitor of DNA Topoisomerase II
Cadmium (Cd(2+)) is a highly toxic and carcinogenic metal that is an environmental and occupational hazard. DNA topoisomerase II is an essential nuclear enzyme and its inhibition can result in formation of genotoxic and recombinogenic DNA double strand breaks. In this study we showed that cadmium ch...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3091975/ https://ncbi.nlm.nih.gov/pubmed/21497582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2011.02.007 |
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