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Cadmium is a Catalytic Inhibitor of DNA Topoisomerase II

Cadmium (Cd(2+)) is a highly toxic and carcinogenic metal that is an environmental and occupational hazard. DNA topoisomerase II is an essential nuclear enzyme and its inhibition can result in formation of genotoxic and recombinogenic DNA double strand breaks. In this study we showed that cadmium ch...

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Bibliografske podrobnosti
Main Authors: Wu, Xing, Yalowich, Jack C., Hasinoff, Brian B.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091975/
https://ncbi.nlm.nih.gov/pubmed/21497582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2011.02.007
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