Discovery of New GPCR biology – One Receptor Structure at a Time

Por Hanson, Michael A., Stevens, Raymond C.
Publicado em 2009

Stabilization of the β2-adrenergic Receptor 4-3-5 Helix Interface by Mutagenesis of Glu-122(3.41), A Critical Residue in GPCR Structure

Por Roth, Christopher B., Hanson, Michael A., Stevens, Raymond C.
Publicado em 2007

LCP-T(m): An Assay to Measure and Understand Stability of Membrane Proteins in a Membrane Environment

Por Liu, Wei, Hanson, Michael A., Stevens, Raymond C., Cherezov, Vadim
Publicado em 2010

Comparisons of optically monitored small-scale stirred tank vessels to optically controlled disposable bag bioreactors

Por Hanson, Michael A, Brorson, Kurt A, Moreira, Antonio R, Rao, Govind
Publicado em 2009

LCP-FRAP Assay for Pre-Screening Membrane Proteins for in Meso Crystallization

Por Cherezov, Vadim, Liu, Jeffrey, Griffith, Mark, Hanson, Michael A., Stevens, Raymond C.
Publicado em 2008

Development of an Automated High Throughput LCP-FRAP Assay to Guide Membrane Protein Crystallization in Lipid Mesophases

Por Xu, Fei, Liu, Wei, Hanson, Michael A., Stevens, Raymond C., Cherezov, Vadim
Publicado em 2011

A Novel Method for Monitoring Monoclonal Antibody Production During Cell Culture

Por Szmacinski, Henryk, Smith, Derek S., Hanson, Michael A., Kostov, Yordan, Lakowicz, Joseph R., Rao, Govind
Publicado em 2008

Analysis of Full and Partial Agonists Binding to β(2)-Adrenergic Receptor Suggests a Role of Transmembrane Helix V in Agonist-Specific Conformational Changes

Por Katritch, Vsevolod, Reynolds, Kimberly A., Cherezov, Vadim, Hanson, Michael A., Roth, Christopher B., Yeager, Mark, Abagyan, Ruben
Publicado em 2009

The 2.6 Å Crystal Structure of a Human A(2A) Adenosine Receptor Bound to an Antagonist

Por Jaakola, Veli-Pekka, Griffith, Mark T., Hanson, Michael A., Cherezov, Vadim, Chien, Ellen Y.T., Lane, J. Robert, Ijzerman, Adriaan P., Stevens, Raymond C.
Publicado em 2008

Biophysical and ion channel functional characterization of the Torpedo californica nicotinic acetylcholine receptor in varying detergent-lipid environments

Por Asmar-Rovira, Guillermo A., Asseo-García, Aloysha M., Quesada, Orestes, Hanson, Michael A., Nogueras, Carlos, Lasalde-Dominicci, José A., Stevens, Raymond C.
Publicado em 2008

A specific cholesterol binding site is established by the 2.8 Å structure of the human β(2)-adrenergic receptor in an alternate crystal form

Por Hanson, Michael A., Cherezov, Vadim, Roth, Christopher B., Griffith, Mark T., Jaakola, Veli-Pekka, Chien, Ellen Y. T., Velasquez, Jeffrey, Kuhn, Peter, Stevens, Raymond C.
Publicado em 2008

Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 µm size X-ray synchrotron beam

Por Cherezov, Vadim, Hanson, Michael A., Griffith, Mark T., Hilgart, Mark C., Sanishvili, Ruslan, Nagarajan, Venugopalan, Stepanov, Sergey, Fischetti, Robert F., Kuhn, Peter, Stevens, Raymond C.
Publicado em 2009

Fusion Partner Toolchest for the Stabilization and Crystallization of G Protein-Coupled Receptors

Por Chun, Eugene, Thompson, Aaron A., Liu, Wei, Roth, Christopher B., Griffith, Mark T., Katritch, Vsevolod, Kunken, Joshua, Xu, Fei, Cherezov, Vadim, Hanson, Michael A., Stevens, Raymond C.
Publicado em 2012

Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist

Por Chien, Ellen Y.T., Liu, Wei, Zhao, Qiang, Katritch, Vsevolod, Han, Gye Won, Hanson, Michael A., Shi, Lei, Newman, Amy Hauck, Javitch, Jonathan A., Cherezov, Vadim, Stevens, Raymond C.
Publicado em 2010

Structural Determinants of Binding the Seven-transmembrane Domain of the Glucagon-like Peptide-1 Receptor (GLP-1R)

Por Yang, Dehua, de Graaf, Chris, Yang, Linlin, Song, Gaojie, Dai, Antao, Cai, Xiaoqing, Feng, Yang, Reedtz-Runge, Steffen, Hanson, Michael A., Yang, Huaiyu, Jiang, Hualiang, Stevens, Raymond C., Wang, Ming-Wei
Publicado no J Biol Chem (2016)

High Resolution Crystal Structure of an Engineered Human β(2)-Adrenergic G protein-Coupled Receptor

Por Cherezov, Vadim, Rosenbaum, Daniel M., Hanson, Michael A., Rasmussen, Søren G. F., Thian, Foon Sun, Kobilka, Tong Sun, Choi, Hee-Jung, Kuhn, Peter, Weis, William I., Kobilka, Brian K., Stevens, Raymond C.
Publicado em 2007

Profiling of membrane protein variants in a baculovirus system by coupling cell-surface detection with small-scale parallel expression

Por Hanson, Michael A., Brooun, Alexei, Baker, Kent A., Jaakola, Veli-Pekka, Roth, Chris, Chien, Ellen, Alexandrov, Alexander, Velasquez, Jeffrey, Davis, Leila, Griffith, Mark, Moy, Kin, Ganser-Pornillos, Barbie, Kuhn, Peter, Ellis, Sam, Yeager, Mark, Stevens, Raymond C.
Publicado em 2007

Crystal Structure of a Lipid G protein-Coupled Receptor

Por Hanson, Michael A., Roth, Christopher B., Jo, Euijung, Griffith, Mark T., Scott, Fiona L., Reinhart, Greg, Desale, Hans, Clemons, Bryan, Cahalan, Stuart M., Schuerer, Stephan C., Sanna, M. Germana, Han, Gye Won, Kuhn, Peter, Rosen, Hugh, Stevens, Raymond C.
Publicado em 2012

Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1

Por Chrencik, Jill E., Roth, Christopher B., Terakado, Masahiko, Kurata, Haruto, Omi, Rie, Kihara, Yasuyuki, Warshaviak, Dora, Nakade, Shinji, Asmar-Rovira, Guillermo, Mileni, Mauro, Mizuno, Hirotaka, Griffith, Mark T., Rodgers, Caroline, Han, Gye Won, Velasquez, Jeffrey, Chun, Jerold, Stevens, Raymond C., Hanson, Michael A.
Publicado no Cell (2015)

Crystal structure of misoprostol bound to the labor inducer prostaglandin E(2) receptor

Por Audet, Martin, White, Kate L., Breton, Billy, Zarzycka, Barbara, Han, Gye Won, Lu, Yan, Gati, Cornelius, Batyuk, Alexander, Popov, Petr, Velasquez, Jeffrey, Manahan, David, Hu, Hao, Weierstall, Uwe, Liu, Wei, Shui, Wenqing, Katritch, Vsevolod, Cherezov, Vadim, Hanson, Michael A., Stevens, Raymond C.
Publicado no Nat Chem Biol (2018)