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Discovery of New GPCR biology – One Receptor Structure at a Time
G protein-coupled receptors (GPCRs) are the largest family of proteins in the human genome. They transmit an exogenous signal to the intracellular second messenger cascade by ligand induced conformational changes within a common seven transmembrane helical bundle. Due to their critical role in biolo...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2813843/ https://ncbi.nlm.nih.gov/pubmed/19141277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.12.003 |
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