Crystal Structure of a Lipid G protein-Coupled Receptor

The lyso-phospholipid sphingosine 1-phosphate modulates lymphocyte trafficking, endothelial development and integrity, heart rate, and vascular tone and maturation by activating G-protein-coupled sphingosine 1-phosphate receptors. Here we present the crystal structure of the sphingosine 1-phosphate...

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Detalhes bibliográficos
Main Authors: Hanson, Michael A., Roth, Christopher B., Jo, Euijung, Griffith, Mark T., Scott, Fiona L., Reinhart, Greg, Desale, Hans, Clemons, Bryan, Cahalan, Stuart M., Schuerer, Stephan C., Sanna, M. Germana, Han, Gye Won, Kuhn, Peter, Rosen, Hugh, Stevens, Raymond C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338336/
https://ncbi.nlm.nih.gov/pubmed/22344443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1215904
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