Crystal Structure of a Lipid G protein-Coupled Receptor

The lyso-phospholipid sphingosine 1-phosphate modulates lymphocyte trafficking, endothelial development and integrity, heart rate, and vascular tone and maturation by activating G-protein-coupled sphingosine 1-phosphate receptors. Here we present the crystal structure of the sphingosine 1-phosphate...

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Bibliografiske detaljer
Main Authors: Hanson, Michael A., Roth, Christopher B., Jo, Euijung, Griffith, Mark T., Scott, Fiona L., Reinhart, Greg, Desale, Hans, Clemons, Bryan, Cahalan, Stuart M., Schuerer, Stephan C., Sanna, M. Germana, Han, Gye Won, Kuhn, Peter, Rosen, Hugh, Stevens, Raymond C.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338336/
https://ncbi.nlm.nih.gov/pubmed/22344443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1215904
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