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Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist
Dopamine modulates movement, cognitive, and emotional functions of the brain through activation of dopamine receptors that belong to the G protein-coupled receptor (GPCR) superfamily. Here we present the crystal structure of the human dopamine D3 receptor (D3R) in complex with the small molecule D2R...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3058422/ https://ncbi.nlm.nih.gov/pubmed/21097933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1197410 |
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