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High Resolution Crystal Structure of an Engineered Human β(2)-Adrenergic G protein-Coupled Receptor
G protein-coupled receptors comprise the largest family of eukaryotic signal transduction proteins that communicate across the membrane. We report the crystal structure of a human β(2)-adrenergic receptor—T4 lysozyme fusion protein bound to the partial inverse agonist carazolol at 2.4 Å resolution....
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2583103/ https://ncbi.nlm.nih.gov/pubmed/17962520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1150577 |
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