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Fusion Partner Toolchest for the Stabilization and Crystallization of G Protein-Coupled Receptors
Structural studies of human G protein-coupled receptors (GPCRs) have recently been accelerated through the use of the T4 lysozyme fusion partner that was inserted into the third intracellular loop. Using chimeras of the human β(2)-adrenergic and human A(2A) adenosine receptors, we present the method...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3375611/ https://ncbi.nlm.nih.gov/pubmed/22681902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.04.010 |
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