The outermost lysine in the S4 of domain III contributes little to the gating charge in sodium channels.

Por Sheets, Michael F, Hanck, Dorothy A
Publicado em 2002

Charge immobilization of the voltage sensor in domain IV is independent of sodium current inactivation

Por Sheets, Michael F, Hanck, Dorothy A
Publicado em 2005

Site-3 Toxins and Cardiac Sodium Channels

Por Hanck, Dorothy A., Sheets, Michael F.
Publicado em 2006

Outward stabilization of the S4 segments in domains III and IV enhances lidocaine block of sodium channels

Por Sheets, Michael F, Hanck, Dorothy A
Publicado em 2007

Molecular Action of Lidocaine on the Voltage Sensors of Sodium Channels

Por Sheets, Michael F., Hanck, Dorothy A.
Publicado em 2003

Gating of skeletal and cardiac muscle sodium channels in mammalian cells

Por Sheets, Michael F, Hanck, Dorothy A
Publicado em 1999

The Relationship between Single-Channel and Whole-Cell Conductance in the T-type Ca(2+) Channel Ca(V)3.1

Por Bittner, Katie C., Hanck, Dorothy A.
Publicado em 2008

Augmentation of Recovery from Inactivation by Site-3 Na Channel Toxins : A Single-Channel and Whole-Cell Study of Persistent Currents

Por Richard Benzinger, G., Tonkovich, Gayle S., Hanck, Dorothy A.
Publicado em 1999

Lidocaine partially depolarizes the S4 segment in domain IV of the sodium channel

Por Sheets, Michael F., Chen, Tiehua, Hanck, Dorothy A.
Publicado em 2010

The Role of the Putative Inactivation Lid in Sodium Channel Gating Current Immobilization

Por Sheets, Michael F., Kyle, John W., Hanck, Dorothy A.
Publicado em 2000

Evidence for multiple effects of ProTxII on activation gating in Na(V)1.5

Por Edgerton, Gabrielle B., Blumenthal, Kenneth M., Hanck, Dorothy A.
Publicado em 2008

Inhibition of the activation pathway of the T-type calcium channel Ca(V)3.1 by ProTxII

Por Edgerton, Gabrielle B., Blumenthal, Kenneth M., Hanck, Dorothy A.
Publicado em 2010

The Sodium Channel as a Target for Local Anesthetic Drugs

Por Fozzard, Harry A., Sheets, Michael F., Hanck, Dorothy A.
Publicado em 2011

A molecular model of the inner pore of the Ca channel in its open state

Por Lipkind, Gregory M, Fozzard, Harry A, Hanck, Dorothy A
Publicado em 2011

Important Role of Asparagines in Coupling the Pore and Votage-Sensor Domain in Voltage-Gated Sodium Channels

Por Sheets, Michael F., Fozzard, Harry A., Hanck, Dorothy A.
Publicado no Biophys J (2015)

Polyvalent Cations Constitute the Voltage Gating Particle in Human Connexin37 Hemichannels

Por Puljung, Michael C., Berthoud, Viviana M., Beyer, Eric C., Hanck, Dorothy A.
Publicado em 2004

Sodium Channel Molecular Conformations and Antiarrhythmic Drug Affinity

Por Sheets, Michael F., Fozzard, Harry A., Lipkind, Gregory M., Hanck, Dorothy A.
Publicado em 2010

Verapamil Block of T-Type Calcium Channels

Por Bergson, Pamela, Lipkind, Gregory, Lee, Steven P., Duban, Mark-Eugene, Hanck, Dorothy A.
Publicado em 2011

Accessibility of mid-segment domain IV S6 residues of the voltage-gated Na(+) channel to methanethiosulfonate reagents

Por Sunami, Akihiko, Tracey, Arlene, Glaaser, Ian W, Lipkind, Gregory M, Hanck, Dorothy A, Fozzard, Harry A
Publicado em 2004

Using Lidocaine and Benzocaine to Link Sodium Channel Molecular Conformations to State-Dependent Antiarrhythmic Drug Affinity

Por Hanck, Dorothy A., Nikitina, Elena, McNulty, Megan M., Fozzard, Harry A., Lipkind, Gregory M., Sheets, Michael F.
Publicado em 2009