Lanean...

The outermost lysine in the S4 of domain III contributes little to the gating charge in sodium channels.

We investigated the contribution the four outermost basic residues (K1, R2, R3, R4) in segment 4 of domain III in the human cardiac Na channel (hH1a, Na(V)1.5) to the total gating charge (Q(max)). Each of the four basic residues were mutated individually to a cysteine. In addition, R2 was also mutat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sheets, Michael F, Hanck, Dorothy A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2002
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302092/
https://ncbi.nlm.nih.gov/pubmed/12023227
Etiketak: Etiketa erantsi
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