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Sodium Channel Molecular Conformations and Antiarrhythmic Drug Affinity
Class I cardiac antiarrhythmic drugs, e.g. lidocaine, mexiletine, flecainide, quinidine, and procainamide, continue to play an important role in the therapy of cardiac arrhythmias because of the presence of use-dependent block. Lidocaine, as well as related drugs like mepivacaine, bupivacaine, and c...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917343/ https://ncbi.nlm.nih.gov/pubmed/20685573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcm.2010.03.002 |
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