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Site-3 Toxins and Cardiac Sodium Channels

Site-3 toxins are small polypeptide venoms from scorpions, sea anemones, and spiders that bind with a high specificity to the extracellular surface of voltage-gated Na channels. After binding to a site near the S4 segment in domain IV the toxin causes disruption of the normal fast inactivation trans...

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Bibliografiska uppgifter
Huvudupphovsmän: Hanck, Dorothy A., Sheets, Michael F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852437/
https://ncbi.nlm.nih.gov/pubmed/17092528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxicon.2006.09.017
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