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Site-3 Toxins and Cardiac Sodium Channels
Site-3 toxins are small polypeptide venoms from scorpions, sea anemones, and spiders that bind with a high specificity to the extracellular surface of voltage-gated Na channels. After binding to a site near the S4 segment in domain IV the toxin causes disruption of the normal fast inactivation trans...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852437/ https://ncbi.nlm.nih.gov/pubmed/17092528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxicon.2006.09.017 |
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