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Evidence for multiple effects of ProTxII on activation gating in Na(V)1.5
The peptide toxin ProTxII, recently isolated from the venom of the tarantula spider Thrixopelma pruriens, modifies gating in voltage-gated Na(+) and Ca(2+) channels. ProTxII is distinct from other known Na(+) channel gating modifier toxins in that it affects activation, but not inactivation. It shif...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2613288/ https://ncbi.nlm.nih.gov/pubmed/18657562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxicon.2008.06.023 |
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