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Inhibition of the activation pathway of the T-type calcium channel Ca(V)3.1 by ProTxII
Toxins have been used extensively to probe the gating mechanisms of voltage-gated ion channels. Relatively few such tools are available to study the low-voltage activated T-type Ca channels, which underlie thalamic neuron firing and affect sleep, resistance to seizures, and weight gain. Here we show...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2909376/ https://ncbi.nlm.nih.gov/pubmed/20600227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxicon.2010.06.009 |
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