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Inhibition of the activation pathway of the T-type calcium channel Ca(V)3.1 by ProTxII

Toxins have been used extensively to probe the gating mechanisms of voltage-gated ion channels. Relatively few such tools are available to study the low-voltage activated T-type Ca channels, which underlie thalamic neuron firing and affect sleep, resistance to seizures, and weight gain. Here we show...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Edgerton, Gabrielle B., Blumenthal, Kenneth M., Hanck, Dorothy A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909376/
https://ncbi.nlm.nih.gov/pubmed/20600227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxicon.2010.06.009
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