Accessibility of mid-segment domain IV S6 residues of the voltage-gated Na(+) channel to methanethiosulfonate reagents

The inner pore of the voltage-gated Na(+) channel is predicted by the structure of bacterial potassium channels to be lined with the four S6 α-helical segments. Our previously published model of the closed pore based on the KcsA structure, and our new model of the open pore based on the MthK structu...

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Detalhes bibliográficos
Main Authors: Sunami, Akihiko, Tracey, Arlene, Glaaser, Ian W, Lipkind, Gregory M, Hanck, Dorothy A, Fozzard, Harry A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665359/
https://ncbi.nlm.nih.gov/pubmed/15579536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.067579
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