How to Culture, Record and Stimulate Neuronal Networks on Micro-electrode Arrays (MEAs)

Por Hales, Chadwick M., Rolston, John D., Potter, Steve M.
Publicado em 2010

Fat mass and obesity-associated (FTO) protein interacts with CaMKII and modulates the activity of CREB signaling pathway

Por Lin, Li, Hales, Chadwick M., Garber, Kathryn, Jin, Peng
Publicado em 2014

Stimulus-evoked high frequency oscillations are present in neuronal networks on microelectrode arrays

Por Hales, Chadwick M., Zeller-Townson, Riley, Newman, Jonathan P., Shoemaker, James T., Killian, Nathan J., Potter, Steve M.
Publicado em 2012

MARK2/EMK1/Par-1Bα Phosphorylation of Rab11-Family Interacting Protein 2 Is Necessary for the Timely Establishment of Polarity in Madin-Darby Canine Kidney Cells

Por Ducharme, Nicole A., Hales, Chadwick M., Lapierre, Lynne A., Ham, Amy-Joan L., Oztan, Asli, Apodaca, Gerard, Goldenring, James R.
Publicado em 2006

Integrated Approaches for Analyzing U1-70K Cleavage in Alzheimer’s Disease

Por Bai, Bing, Chen, Ping-Chung, Hales, Chadwick M., Wu, Zhiping, Pagala, Vishwajeeth, High, Anthony A., Levey, Allan I., Lah, James J., Peng, Junmin
Publicado no J Proteome Res (2014)

Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration

Por Xu, Zihui, Poidevin, Mickael, Li, Xuekun, Li, Yujing, Shu, Liqi, Nelson, David L., Li, He, Hales, Chadwick M., Gearing, Marla, Wingo, Thomas S., Jin, Peng
Publicado em 2013

Aggregates of Small Nuclear Ribonucleic Acids (snRNAs) in Alzheimer's Disease

Por Hales, Chadwick M., Dammer, Eric B., Diner, Ian, Yi, Hong, Seyfried, Nicholas T., Gearing, Marla, Glass, Jonathan D., Montine, Thomas J., Levey, Allan I., Lah, James J.
Publicado em 2014

Myosin Vb Is Associated with Plasma Membrane Recycling Systems

Por Lapierre, Lynne A., Kumar, Ravindra, Hales, Chadwick M., Navarre, Jennifer, Bhartur, Sheela G., Burnette, Jason O., Provance, D. William, Mercer, John A., Bähler, Martin, Goldenring, James R.
Publicado em 2001

U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer’s disease due to autosomal dominant genetic mutations and trisomy 21

Por Hales, Chadwick M, Seyfried, Nicholas T, Dammer, Eric B, Duong, Duc, Yi, Hong, Gearing, Marla, Troncoso, Juan C, Mufson, Elliott J, Thambisetty, Madhav, Levey, Allan I, Lah, James J
Publicado em 2014

A human pluripotent stem cell model of catecholaminergic polymorphic ventricular tachycardia recapitulates patient-specific drug responses

Por Preininger, Marcela K., Jha, Rajneesh, Maxwell, Joshua T., Wu, Qingling, Singh, Monalisa, Wang, Bo, Dalal, Aarti, Mceachin, Zachary T., Rossoll, Wilfried, Hales, Chadwick M., Fischbach, Peter S., Wagner, Mary B., Xu, Chunhui
Publicado no Dis Model Mech (2016)

Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer’s Disease progression

Por Hales, Chadwick M., Dammer, Eric B., Deng, Qiudong, Duong, Duc M., Gearing, Marla, Troncoso, Juan C., Thambisetty, Madhav, Lah, James J., Shulman, Joshua M., Levey, Allan I., Seyfried, Nicholas T.
Publicado no Proteomics (2016)

Aggregation Properties of the Small Nuclear Ribonucleoprotein U1-70K in Alzheimer Disease

Por Diner, Ian, Hales, Chadwick M., Bishof, Isaac, Rabenold, Lake, Duong, Duc M., Yi, Hong, Laur, Oskar, Gearing, Marla, Troncoso, Juan, Thambisetty, Madhav, Lah, James J., Levey, Allan I., Seyfried, Nicholas T.
Publicado no J Biol Chem (2014)

Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia

Por Holler, Christopher J., Taylor, Georgia, McEachin, Zachary T., Deng, Qiudong, Watkins, William J., Hudson, Kathryn, Easley, Charles A., Hu, William T., Hales, Chadwick M., Rossoll, Wilfried, Bassell, Gary J., Kukar, Thomas
Publicado no Mol Neurodegener (2016)

Abnormal Gephyrin Immunoreactivity Associated with Alzheimer’s Disease Pathologic Changes

Por Hales, Chadwick M., Rees, Howard, Seyfried, Nicholas T., Dammer, Eric B., Duong, Duc M., Gearing, Marla, Montine, Thomas J., Troncoso, Juan C., Thambisetty, Madhav, Levey, Allan I., Lah, James J, Wingo, Thomas S.
Publicado em 2013

CSF complement 3 and factor H are staging biomarkers in Alzheimer’s disease

Por Hu, William T., Watts, Kelly D., Tailor, Prashant, Nguyen, Trung P., Howell, Jennifer C., Lee, Raven C., Seyfried, Nicholas T., Gearing, Marla, Hales, Chadwick M., Levey, Allan I., Lah, James J., Lee, Eva K.
Publicado no Acta Neuropathol Commun (2016)

Pharmacologic Inhibition of ROCK2 Suppresses Amyloid-β Production in an Alzheimer's Disease Mouse Model

Por Herskowitz, Jeremy H., Feng, Yangbo, Mattheyses, Alexa L., Hales, Chadwick M., Higginbotham, Lenora A., Duong, Duc M., Montine, Thomas J., Troncoso, Juan C., Thambisetty, Madhav, Seyfried, Nicholas T., Levey, Allan I., Lah, James J.
Publicado em 2013

Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients

Por Konrad, Csaba, Kawamata, Hibiki, Bredvik, Kirsten G., Arreguin, Andrea J., Cajamarca, Steven A., Hupf, Jonathan C., Ravits, John M., Miller, Timothy M., Maragakis, Nicholas J., Hales, Chadwick M., Glass, Jonathan D., Gross, Steven, Mitsumoto, Hiroshi, Manfredi, Giovanni
Publicado no Mol Neurodegener (2017)

A Multi-Network Approach Identifies Protein-specific Co-expression in Asymptomatic and Symptomatic Alzheimer’s Disease

Por Seyfried, Nicholas T., Dammer, Eric B., Swarup, Vivek, Nandakumar, Divya, Duong, Duc M., Yin, Luming, Deng, Qiudong, Nguyen, Tram, Hales, Chadwick M., Wingo, Thomas, Glass, Jonathan, Gearing, Marla, Thambisetty, Madhav, Troncoso, Juan C., Geschwind, Daniel H., Lah, James J., Levey, Allan I.
Publicado no Cell Syst (2016)

U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer’s disease

Por Bai, Bing, Hales, Chadwick M., Chen, Ping-Chung, Gozal, Yair, Dammer, Eric B., Fritz, Jason J., Wang, Xusheng, Xia, Qiangwei, Duong, Duc M., Street, Craig, Cantero, Gloria, Cheng, Dongmei, Jones, Drew R., Wu, Zhiping, Li, Yuxin, Diner, Ian, Heilman, Craig J., Rees, Howard D., Wu, Hao, Lin, Li, Szulwach, Keith E., Gearing, Marla, Mufson, Elliott J., Bennett, David A., Montine, Thomas J., Seyfried, Nicholas T., Wingo, Thomas S., Sun, Yi E., Jin, Peng, Hanfelt, John, Willcock, Donna M., Levey, Allan, Lah, James J., Peng, Junmin
Publicado em 2013